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Simulation of Transcatheter Aortic Valve Implantation under Consideration of Leaflet Calcification

Christoph Russ, Raoul Hopf, Sven Hirsch, Simon S√ľndermann, Volkmar Falk, Gabor Székely, Michael Gessat
IEEE Engineering in Medicine and Biology Conference
Osaka, Japan 2013, in press


Transcatheter aortic valve implantation (TAVI) is a minimally invasive off-pump procedure to replace diseased aortic heart valves. Known complications include paravalvular leaks, atrioventricular blocks, coronary obstruction and annu- lar rupture. Careful procedure planning including appropriate stent selection and sizing are crucial. Few patient-specific geo- metric parameters, like annular diameters, annular perimeter and measurement of the distance to the coronary ostia, are currently used within this process. Biomechanical simulation allows the consideration of extracted anatomy and material parameters for the intervention, which may improve planning and execution phases. We present a simulation workflow using a fully segmented aortic root anatomy, which was extracted from pre-operative CT-scan data and apply individual material models and parameters to predict the procedure outcome. Our results indicate the high relevance of calcification location and size for intervention planning, which are not sufficiently considered at this time. Our analysis can further provide guidance for accurate, patient-specific device positioning and future adaptations to stent design.

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  author = {Christoph Russ and Raoul Hopf and Sven Hirsch and Simon S\"undermann and Volkmar Falk and Gabor Székely and Michael Gessat},
  title = {Simulation of Transcatheter Aortic Valve Implantation under Consideration of Leaflet Calcification},
  booktitle = {IEEE Engineering in Medicine and Biology Conference},
  year = {2013},
  pages = {711-714},
  keywords = {biomedical simulation, heart-valve leaflets, calcification},
  note = {in press}