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A Simulation Environment for Validation and Comparison of fMRI Evaluation Procedures

D. Ekatodramis, G. Székely, E. Martin and G. Gerig


Comparison of fMRI results with findings using different modalities such as PET, EEG or MEG on the same person is helpful to test the accuracy of fMRI analysis procedures. Validation, however, can never become complete, as there is no ground truth accurately known for fMRI experiments. The purpose of this work was to build a software environment, where the physiological response function and the experimental parameters of an fMRI experiment can be simulated in a possibly realistic manner and therefore can be controlled. Such artificially produced data sets allow then to test the reliability of analysis methods that are applied on real data with similar experimental conditions.

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  author = {D. Ekatodramis and G. Székely and E. Martin and G. Gerig},
  title = {A Simulation Environment for Validation and Comparison of fMRI Evaluation Procedures},
  booktitle = {NeuroImage},
  year = {1996},
  pages = {57},
  volume = {3},
  keywords = {medical image analysis, simulation, brain, MR imaging}