Applications of Motion Data
Proton Therapy Planning
By using intensity modulated radiotherapy (IMRT) and especially intensity modulated proton therapy (IMPT),
highly conformal dose distributions can be delivered to a tumour. With the obtained motion data,
different delivery methodologies are evaluated with respect to motion sensitivity in order to study the interaction
between time-varying delivery and realistic respiratory motion.
|A hypothetic tumour is animated according to the obtained motion data.
A simple one-field proton therapy plan shows the effect of this motion
on the dose distribution.
Although the reconstructed MR images cannot be used directly for dose calculations,
the deformation vectors resulting from the motion estimation are independent of the imaging modality.
These motion vectors can be used to deform planning CT images or the displacement vectors can be integrated directly
into the dynamic dose calculation.
||A CT volume was animated according to
the motionfield determined from 4DMRI of the same patient.
Evaluation of Gating Methods
Potential gating techniques for radiation therapy and MRI guided Focused Ultrasound (MRgFUS),
which are applicable in real-time,
are currently being evaluated with respect to residual motion and optimal placement of surrogates.
|Point positions without and with gating (30% duty cycle)
Training and Planning of RF Ablation
The obtained data will be used to build generic models of shape and motion of the liver. The models will be intregrated into a
for radiofrequency (RF) ablation of liver tumours.